Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology

The proliferation and activation of microglial cells is a hallmark of several neurodegenerative conditions. This mechanism is regulated by the activation of the colony-stimulating factor 1 receptor (CSF1R), thus providing a target that may prevent the progression of conditions such as Alzheimer’s di...

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Detalles Bibliográficos
Autores principales: Olmos-Alonso, Adrian, Schetters, Sjoerd T. T., Sri, Sarmi, Askew, Katharine, Mancuso, Renzo, Vargas-Caballero, Mariana, Holscher, Christian, Perry, V. Hugh, Gomez-Nicola, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766375/
https://www.ncbi.nlm.nih.gov/pubmed/26747862
http://dx.doi.org/10.1093/brain/awv379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766375/
https://www.ncbi.nlm.nih.gov/pubmed/26747862
http://dx.doi.org/10.1093/brain/awv379

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