The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR

Optimal fetal lung growth requires anion-driven fluid secretion into the lumen of the developing organ. The fetus is hypercalcemic compared to the mother and here we show that in the developing human lung this hypercalcaemia acts on the extracellular calcium-sensing receptor, CaSR, to promote fluid-...

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Detalles Bibliográficos
Autores principales: Brennan, Sarah C., Wilkinson, William J., Tseng, Hsiu-Er, Finney, Brenda, Monk, Bethan, Dibble, Holly, Quilliam, Samantha, Warburton, David, Galietta, Luis J., Kemp, Paul J., Riccardi, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766410/
https://www.ncbi.nlm.nih.gov/pubmed/26911344
http://dx.doi.org/10.1038/srep21975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766410/
https://www.ncbi.nlm.nih.gov/pubmed/26911344
http://dx.doi.org/10.1038/srep21975

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