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Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet

Maternal obesity is associated with increased risk of developing diabetes, obesity and premature death in adult offspring. Mid-life diabetes, hypertension and hypercholesterolaemia are risk factors for the development of sporadic Alzheimer’s disease (AD). A key pathogenic feature of AD is the accumu...

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Detalles Bibliográficos
Autores principales: Nizari, Shereen, Carare, Roxana O., Hawkes, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766411/
https://www.ncbi.nlm.nih.gov/pubmed/26911528
http://dx.doi.org/10.1038/srep21981