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Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet
Maternal obesity is associated with increased risk of developing diabetes, obesity and premature death in adult offspring. Mid-life diabetes, hypertension and hypercholesterolaemia are risk factors for the development of sporadic Alzheimer’s disease (AD). A key pathogenic feature of AD is the accumu...
Autores principales: | Nizari, Shereen, Carare, Roxana O., Hawkes, Cheryl A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766411/ https://www.ncbi.nlm.nih.gov/pubmed/26911528 http://dx.doi.org/10.1038/srep21981 |
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