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Opposing roles of LTB(4) and PGE(2) in regulating the inflammasome-dependent scorpion venom-induced mortality

Tityus serrulatus sting causes thousands of deaths annually worldwide. T. serrulatus-envenomed victims exhibit local or systemic reaction that culminates in pulmonary oedema, potentially leading to death. However, the molecular mechanisms underlying T. serrulatus venom (TsV) activity remain unknown....

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Detalles Bibliográficos
Autores principales: Zoccal, Karina F., Sorgi, Carlos A., Hori, Juliana I., Paula-Silva, Francisco W. G., Arantes, Eliane C., Serezani, Carlos H., Zamboni, Dario S., Faccioli, Lúcia H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766425/
https://www.ncbi.nlm.nih.gov/pubmed/26907476
http://dx.doi.org/10.1038/ncomms10760