Cargando…
Opposing roles of LTB(4) and PGE(2) in regulating the inflammasome-dependent scorpion venom-induced mortality
Tityus serrulatus sting causes thousands of deaths annually worldwide. T. serrulatus-envenomed victims exhibit local or systemic reaction that culminates in pulmonary oedema, potentially leading to death. However, the molecular mechanisms underlying T. serrulatus venom (TsV) activity remain unknown....
Autores principales: | Zoccal, Karina F., Sorgi, Carlos A., Hori, Juliana I., Paula-Silva, Francisco W. G., Arantes, Eliane C., Serezani, Carlos H., Zamboni, Dario S., Faccioli, Lúcia H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766425/ https://www.ncbi.nlm.nih.gov/pubmed/26907476 http://dx.doi.org/10.1038/ncomms10760 |
Ejemplares similares
-
Partial purification and functional characterization of Ts19 Frag-I, a novel toxin from Tityus serrulatus scorpion venom
por: Lima, Priscila C., et al.
Publicado: (2015) -
Paradoxical Effect of LTB(4) on the Regulation of Stress-Induced Corticosterone Production
por: Locachevic, Gisele A., et al.
Publicado: (2019) -
Unbalanced production of LTB(4)/PGE(2) driven by diabetes increases susceptibility to cutaneous leishmaniasis
por: Bonyek-Silva, Icaro, et al.
Publicado: (2020) -
EP80317 Restrains Inflammation and Mortality Caused by Scorpion Envenomation in Mice
por: Zoccal, Karina F., et al.
Publicado: (2019) -
Interleukin-1 receptor-induced PGE(2) production controls acetylcholine-mediated cardiac dysfunction and mortality during scorpion envenomation
por: Reis, Mouzarllem B., et al.
Publicado: (2020)