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Differential expression of p38 MAPK α, β, γ, δ isoforms in nucleus pulposus modulates macrophage polarization in intervertebral disc degeneration

P38MAPK mediates cytokine induced inflammation in nucleus pulposus (NP) cells and involves in multiple cellular processes which are related to intervertebral disc degeneration (IDD). The aim of this study was to investigate the expression, activation and function of p38 MAPK isoforms (α,β, γ and δ)...

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Detalles Bibliográficos
Autores principales: Yang, Chen, Cao, Peng, Gao, Yang, Wu, Ming, Lin, Yun, Tian, Ye, Yuan, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766431/
https://www.ncbi.nlm.nih.gov/pubmed/26911458
http://dx.doi.org/10.1038/srep22182