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Truncation of C-terminal 20 amino acids in PA-X contributes to adaptation of swine influenza virus in pigs

The PA-X protein is a fusion protein incorporating the N-terminal 191 amino acids of the PA protein with a short C-terminal sequence encoded by an overlapping ORF (X-ORF) in segment 3 that is accessed by + 1 ribosomal frameshifting, and this X-ORF exists in either full length or a truncated form (ei...

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Detalles Bibliográficos
Autores principales: Xu, Guanlong, Zhang, Xuxiao, Sun, Yipeng, Liu, Qinfang, Sun, Honglei, Xiong, Xin, Jiang, Ming, He, Qiming, Wang, Yu, Pu, Juan, Guo, Xin, Yang, Hanchun, Liu, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766433/
https://www.ncbi.nlm.nih.gov/pubmed/26912401
http://dx.doi.org/10.1038/srep21845