Cdk12 Is A Gene-Selective RNA Polymerase II Kinase That Regulates a Subset of the Transcriptome, Including Nrf2 Target Genes

The Nrf2 transcription factor is well conserved throughout metazoan evolution and serves as a central regulator of adaptive cellular responses to oxidative stress. We carried out an RNAi screen in Drosophila S2 cells to better understand the regulatory mechanisms governing Nrf2 target gene expressio...

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Detalles Bibliográficos
Autores principales: Li, Xuan, Chatterjee, Nirmalya, Spirohn, Kerstin, Boutros, Michael, Bohmann, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766476/
https://www.ncbi.nlm.nih.gov/pubmed/26911346
http://dx.doi.org/10.1038/srep21455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766476/
https://www.ncbi.nlm.nih.gov/pubmed/26911346
http://dx.doi.org/10.1038/srep21455

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