Thyroid Transcription Factor 1 Reprograms Angiogenic Activities of Secretome

Through both gain- and loss-of-TTF-1 expression strategies, we show that TTF-1 positively regulates vascular endothelial growth factor (VEGF) and that the VEGF promoter element contains multiple TTF-1-responsive sequences. The major signaling receptor for VEGF, i.e VEGFR2, also appears to be under a...

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Detalles Bibliográficos
Autores principales: Wood, Lauren W., Cox, Nicole I., Phelps, Cody A., Lai, Shao-Chiang, Poddar, Arjun, Talbot, Conover, Mu, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766481/
https://www.ncbi.nlm.nih.gov/pubmed/26912193
http://dx.doi.org/10.1038/srep19857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766481/
https://www.ncbi.nlm.nih.gov/pubmed/26912193
http://dx.doi.org/10.1038/srep19857

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