Spatio-temporal co-ordination of RhoA, Rac1 and Cdc42 activation during prototypical edge protrusion and retraction dynamics

The three canonical Rho GTPases RhoA, Rac1 and Cdc42 co-ordinate cytoskeletal dynamics. Recent studies indicate that all three Rho GTPases are activated at the leading edge of motile fibroblasts, where their activity fluctuates at subminute time and micrometer length scales. Here, we use a microflui...

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Detalles Bibliográficos
Autores principales: Martin, Katrin, Reimann, Andreas, Fritz, Rafael D., Ryu, Hyunryul, Jeon, Noo Li, Pertz, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766498/
https://www.ncbi.nlm.nih.gov/pubmed/26912264
http://dx.doi.org/10.1038/srep21901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766498/
https://www.ncbi.nlm.nih.gov/pubmed/26912264
http://dx.doi.org/10.1038/srep21901

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