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Macrophage-derived Lipocalin-2 contributes to ischemic resistance mechanisms by protecting from renal injury

Renal ischemia-reperfusion injury triggers an inflammatory response associated to infiltrating macrophages which determines the further outcome of disease. Brown Norway rats are known to show endogenous resistance to ischemia-induced renal damage. By contrast, Sprague Dawley rats exhibit a higher su...

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Detalles Bibliográficos
Autores principales: Jung, Michaela, Brüne, Bernhard, Hotter, Georgina, Sola, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766505/
https://www.ncbi.nlm.nih.gov/pubmed/26911537
http://dx.doi.org/10.1038/srep21950