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Nucleus factory on cavitation bubble for amyloid β fibril

Structural evolution from monomer to fibril of amyloid β peptide is related to pathogenic mechanism of Alzheimer disease, and its acceleration is a long-running problem in drug development. This study reveals that ultrasonic cavitation bubbles behave as catalysts for nucleation of the peptide: The n...

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Detalles Bibliográficos
Autores principales: Nakajima, Kichitaro, Ogi, Hirotsugu, Adachi, Kanta, Noi, Kentaro, Hirao, Masahiko, Yagi, Hisashi, Goto, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766559/
https://www.ncbi.nlm.nih.gov/pubmed/26912021
http://dx.doi.org/10.1038/srep22015