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Nucleus factory on cavitation bubble for amyloid β fibril
Structural evolution from monomer to fibril of amyloid β peptide is related to pathogenic mechanism of Alzheimer disease, and its acceleration is a long-running problem in drug development. This study reveals that ultrasonic cavitation bubbles behave as catalysts for nucleation of the peptide: The n...
Autores principales: | Nakajima, Kichitaro, Ogi, Hirotsugu, Adachi, Kanta, Noi, Kentaro, Hirao, Masahiko, Yagi, Hisashi, Goto, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766559/ https://www.ncbi.nlm.nih.gov/pubmed/26912021 http://dx.doi.org/10.1038/srep22015 |
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