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Detection of substrate-dependent conformational changes in the P450 fold by nuclear magnetic resonance
Cytochrome P450 monooxygenases typically catalyze the insertion of one atom of oxygen from O(2) into unactivated carbon-hydrogen and carbon-carbon bonds, with concomitant reduction of the other oxygen atom to H(2)O by NAD(P)H. Comparison of the average structures of the camphor hydroxylase cytochrom...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766564/ https://www.ncbi.nlm.nih.gov/pubmed/26911901 http://dx.doi.org/10.1038/srep22035 |