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The Transcriptional Foundations of Sp110-mediated Macrophage (RAW264.7) Resistance to Mycobacterium tuberculosis H37Ra

Human tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading global health problem, causing 1.3 million deaths each year. The nuclear body protein, Sp110, has been linked to TB resistance and previous work showed that it enhances macrophage apoptosis upon Mtb infection. Her...

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Detalles Bibliográficos
Autores principales: Wu, Yongyan, Guo, Zekun, Yao, Kezhen, Miao, Yue, Liang, Shuxin, Liu, Fayang, Wang, Yongsheng, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766572/
https://www.ncbi.nlm.nih.gov/pubmed/26912204
http://dx.doi.org/10.1038/srep22041