Increased duplex stabilization in porphyrin-LNA zipper arrays with structure dependent exciton coupling

Porphyrins were attached to LNA uridine building blocks via rigid 5-acetylene or more flexible propargyl-amide linkers and incorporated into DNA strands. The systems show a greatly increased thermodynamic stability when using as little as three porphyrins in a zipper arrangement. Thermodynamic analy...

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Detalles Bibliográficos
Autores principales: Singleton, Daniel G., Hussain, Rohanah, Siligardi, Giuliano, Kumar, Pawan, Hrdlicka, Patrick J., Berova, Nina, Stulz, Eugen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766578/
https://www.ncbi.nlm.nih.gov/pubmed/26416024
http://dx.doi.org/10.1039/c5ob01681a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766578/
https://www.ncbi.nlm.nih.gov/pubmed/26416024
http://dx.doi.org/10.1039/c5ob01681a

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