Trienamine catalyzed asymmetric synthesis and biological investigation of a cytochalasin B-inspired compound collection

Due to their enhanced metabolic needs many cancers need a sufficient supply of glucose, and novel inhibitors of glucose import are in high demand. Cytochalasin B (CB) is a potent natural glucose import inhibitor which also impairs the actin cytoskeleton leading to undesired toxicity. With a view to...

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Detalles Bibliográficos
Autores principales: Sellstedt, Magnus, Schwalfenberg, Melanie, Ziegler, Slava, Antonchick, Andrey P., Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766597/
https://www.ncbi.nlm.nih.gov/pubmed/26606903
http://dx.doi.org/10.1039/c5ob02272j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766597/
https://www.ncbi.nlm.nih.gov/pubmed/26606903
http://dx.doi.org/10.1039/c5ob02272j

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