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Trienamine catalyzed asymmetric synthesis and biological investigation of a cytochalasin B-inspired compound collection
Due to their enhanced metabolic needs many cancers need a sufficient supply of glucose, and novel inhibitors of glucose import are in high demand. Cytochalasin B (CB) is a potent natural glucose import inhibitor which also impairs the actin cytoskeleton leading to undesired toxicity. With a view to...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766597/ https://www.ncbi.nlm.nih.gov/pubmed/26606903 http://dx.doi.org/10.1039/c5ob02272j |