Cargando…

Biochemical and functional characterization of Plasmodium falciparum DNA polymerase δ

BACKGROUND: Emergence of drug-resistant Plasmodium falciparum has created an urgent need for new drug targets. DNA polymerase δ is an essential enzyme required for chromosomal DNA replication and repair, and therefore may be a potential target for anti-malarial drug development. However, little is k...

Descripción completa

Detalles Bibliográficos
Autores principales: Vasuvat, Jitlada, Montree, Atcha, Moonsom, Sangduen, Leartsakulpanich, Ubolsree, Petmitr, Songsak, Focher, Federico, Wright, George E., Chavalitshewinkoon-Petmitr, Porntip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766629/
https://www.ncbi.nlm.nih.gov/pubmed/26911594
http://dx.doi.org/10.1186/s12936-016-1166-0