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Biochemical and functional characterization of Plasmodium falciparum DNA polymerase δ
BACKGROUND: Emergence of drug-resistant Plasmodium falciparum has created an urgent need for new drug targets. DNA polymerase δ is an essential enzyme required for chromosomal DNA replication and repair, and therefore may be a potential target for anti-malarial drug development. However, little is k...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766629/ https://www.ncbi.nlm.nih.gov/pubmed/26911594 http://dx.doi.org/10.1186/s12936-016-1166-0 |