Cargando…

Biochemical and functional characterization of Plasmodium falciparum DNA polymerase δ

BACKGROUND: Emergence of drug-resistant Plasmodium falciparum has created an urgent need for new drug targets. DNA polymerase δ is an essential enzyme required for chromosomal DNA replication and repair, and therefore may be a potential target for anti-malarial drug development. However, little is k...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vasuvat, Jitlada, Montree, Atcha, Moonsom, Sangduen, Leartsakulpanich, Ubolsree, Petmitr, Songsak, Focher, Federico, Wright, George E., Chavalitshewinkoon-Petmitr, Porntip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766629/ https://www.ncbi.nlm.nih.gov/pubmed/26911594 http://dx.doi.org/10.1186/s12936-016-1166-0

Ejemplares similares

Characterization of Plasmodium falciparum ATP-dependent DNA helicase RuvB3
por: Limudomporn, Paviga, et al.
Publicado: (2016)

Molecular characterization of Plasmodium falciparum uracil-DNA glycosylase and its potential as a new anti-malarial drug target
por: Suksangpleng, Thidarat, et al.
Publicado: (2014)

Molecular characterization of Plasmodium falciparum DNA-3-methyladenine glycosylase
por: Pinthong, Nattapon, et al.
Publicado: (2020)

Inhibitory effects of anthracyclines on partially purified 5′–3′ DNA helicase of Plasmodium falciparum
por: Rattaprasert, Pongruj, et al.
Publicado: (2022)

Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine
por: Kritsiriwuthinan, Kanyanan, et al.
Publicado: (2011)

Combining isothermal recombinase polymerase amplification with lateral flow assay for diagnosis of P. cynomolgi malaria infection
por: Rattaprasert, Pongruj, et al.
Publicado: (2023)

Suppression of Plasmodium falciparum by serum collected from a case of Plasmodium vivax infection
por: Nagao, Yoshiro, et al.
Publicado: (2008)

Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females
por: Chamchoy, Kamonwan, et al.
Publicado: (2023)

Differential expression of matrix metalloproteinase-13 in association with invasion of breast cancer
por: Kotepui, Manas, et al.
Publicado: (2016)

The structure of Plasmodium falciparum serine hydroxymethyltransferase reveals a novel redox switch that regulates its activities
por: Chitnumsub, Penchit, et al.
Publicado: (2014)

Plasmodium serine hydroxymethyltransferase: indispensability and display of distinct localization
por: Pornthanakasem, Wichai, et al.
Publicado: (2012)

Cloning and heterologous expression of Plasmodium ovale dihydrofolate reductase-thymidylate synthase gene
por: Tirakarn, Srisuda, et al.
Publicado: (2012)

Plasmodium serine hydroxymethyltransferase as a potential anti-malarial target: inhibition studies using improved methods for enzyme production and assay
por: Sopitthummakhun, Kittipat, et al.
Publicado: (2012)

Antifolate Agents Against Wild and Mutant Strains of Plasmodium falciparum
por: Shaikh, M. S., et al.
Publicado: (2014)

Genotype-phenotype association and biochemical analyses of glucose-6-phosphate dehydrogenase variants: Implications for the hemolytic risk of using 8-aminoquinolines for radical cure
por: Sudsumrit, Sirapapha, et al.
Publicado: (2022)

Human Vδ1(+) T Cells in the Immune Response to Plasmodium falciparum Infection
por: Hviid, Lars, et al.
Publicado: (2019)

Biochemical and functional characterization of Plasmodium falciparum GTP cyclohydrolase I
por: Kümpornsin, Krittikorn, et al.
Publicado: (2014)

Biochemical and structural characterization of the apicoplast dihydrolipoamide dehydrogenase of Plasmodium falciparum
por: Laine, Larissa M., et al.
Publicado: (2015)

Application of WST-8 based colorimetric NAD(P)H detection for quantitative dehydrogenase assays
por: Chamchoy, Kamonwan, et al.
Publicado: (2019)

Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase
por: Kaur, Supreet, et al.
Publicado: (2022)

Mutation tendency of mutator Plasmodium berghei with proofreading-deficient DNA polymerase δ
por: Honma, Hajime, et al.
Publicado: (2016)

Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control
por: Chitnumsub, Penchit, et al.
Publicado: (2014)

Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum
por: Boucher, Ian W, et al.
Publicado: (2006)

Expression of a secretory α-glucosidase II from Apis cerana indica in Pichia pastoris and its characterization
por: Kaewmuangmoon, Jirattikarn, et al.
Publicado: (2013)

Functional analysis of BPSS2242 reveals its detoxification role in Burkholderia pseudomallei under salt stress
por: Chamchoy, Kamonwan, et al.
Publicado: (2020)

A novel bicyclic 2,4-diaminopyrimidine inhibitor of Streptococcus suis dihydrofolate reductase
por: Songsungthong, Warangkhana, et al.
Publicado: (2021)

Rapid detection of Plasmodium falciparum with isothermal recombinase polymerase amplification and lateral flow analysis
por: Kersting, Sebastian, et al.
Publicado: (2014)

Biochemical characterization of Plasmodium falciparum parasite specific helicase 1 (PfPSH1)
por: Chauhan, Manish, et al.
Publicado: (2019)

Diaminoquinazoline MMV675968 from Pathogen Box inhibits Acinetobacter baumannii growth through targeting of dihydrofolate reductase
por: Songsungthong, Warangkhana, et al.
Publicado: (2019)

Biochemical Analysis of the Plasmodium falciparum Erythrocyte-binding Antigen-175 (EBA175)-Glycophorin-A Interaction: IMPLICATIONS FOR VACCINE DESIGN
por: Wanaguru, Madushi, et al.
Publicado: (2013)

Combined effects of double mutations on catalytic activity and structural stability contribute to clinical manifestations of glucose-6-phosphate dehydrogenase deficiency
por: Pakparnich, Phonchanan, et al.
Publicado: (2021)

Biochemical and Functional Analysis of Two Plasmodium falciparum Blood-Stage 6-Cys Proteins: P12 and P41
por: Taechalertpaisarn, Tana, et al.
Publicado: (2012)

PDIP46 (DNA polymerase δ interacting protein 46) is an activating factor for human DNA polymerase δ
por: Wang, Xiaoxiao, et al.
Publicado: (2016)

Effect of combinations of antiviral drugs on herpes simplex encephalitis
por: Gebhardt, Bryan M, et al.
Publicado: (2009)

DNA polymerase δ proofreads errors made by DNA polymerase ε
por: Bulock, Chelsea R., et al.
Publicado: (2020)

C22 podovirus infectivity is associated with intermediate stiffness
por: Sae-Ueng, Udom, et al.
Publicado: (2020)

Thermoresponsive C22 phage stiffness modulates the phage infectivity
por: Sae-Ueng, Udom, et al.
Publicado: (2022)

Plasmodium falciparum Erythrocyte Invasion: Combining Function with Immune Evasion
por: Wright, Gavin J., et al.
Publicado: (2014)

Modelling the Incidence of Plasmodium vivax and Plasmodium falciparum Malaria in Afghanistan 2006–2009
por: Alegana, Victor A., et al.
Publicado: (2014)

Assessment of Clinical Diagnosis, Microscopy, Rapid Diagnostic Tests, and Polymerase Chain Reaction in the Diagnosis of Plasmodium falciparum in Nigeria
por: Ojurongbe, Olusola, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_gdjev7s2kh78uigklkj55v0g4l