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IDH mutations may not preclude distant, trans-tentorial spread in gliomas: a case report and review of the literature

BACKGROUND: IDH mutations have been demonstrated to confer prolonged survival in patients suffering from gliomas, but the mechanisms underlying the improved prognosis are unclear. While some studies have attributed these observations to an enhanced sensitivity to genotoxic therapies, others have pos...

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Detalles Bibliográficos
Autores principales: Hong, Christopher S., Hsieh, Jason K., Edwards, Nancy A., Ray-Chaudhury, Abhik, Zaghloul, Kareem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766660/
https://www.ncbi.nlm.nih.gov/pubmed/26911558
http://dx.doi.org/10.1186/s12957-016-0814-8