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Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells

BACKGROUND: For a long time cancer cells are known for increased uptake of glucose and its metabolization through glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key regulatory enzyme of this pathway and can produce ATP through oxidative level of phosphorylation. Previously, we rep...

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Detalles Bibliográficos
Autores principales: Das, Mahua R., Bag, Arup K., Saha, Shekhar, Ghosh, Alok, Dey, Sumit K., Das, Provas, Mandal, Chitra, Ray, Subhankar, Chakrabarti, Saikat, Ray, Manju, Jana, Siddhartha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766697/
https://www.ncbi.nlm.nih.gov/pubmed/26911935
http://dx.doi.org/10.1186/s12885-016-2172-x