Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease

BACKGROUND: Human papillomavirus (HPV) has been identified as the primary etiologic factor of cervical cancer as well as subsets of anogenital and oropharyngeal cancers. The two HPV viral oncoproteins, E6 and E7, are uniquely and consistently expressed in all HPV infected cells and are therefore pro...

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Detalles Bibliográficos
Autores principales: Peng, Shiwen, Qiu, Jin, Yang, Andrew, Yang, Benjamin, Jeang, Jessica, Wang, Joshua W., Chang, Yung-Nien, Brayton, Cory, Roden, Richard B. S., Hung, Chien-Fu, Wu, T.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766698/
https://www.ncbi.nlm.nih.gov/pubmed/26918115
http://dx.doi.org/10.1186/s13578-016-0080-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766698/
https://www.ncbi.nlm.nih.gov/pubmed/26918115
http://dx.doi.org/10.1186/s13578-016-0080-z

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