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Efficient therapy of ischaemic lesions with VEGF(121)-fibrin in an animal model of systemic sclerosis

BACKGROUND: In systemic sclerosis (SSc), chronic and uncontrolled overexpression of vascular endothelial growth factor (VEGF) results in chaotic vessels, and intractable fingertip ulcers. Vice versa, VEGF is a potent mediator of angiogenesis if temporally and spatially controlled. We have addressed...

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Detalles Bibliográficos
Autores principales: Allipour Birgani, Shadab, Mailänder, Marion, Wasle, Ines, Dietrich, Hermann, Gruber, Johann, Distler, Oliver, Sgonc, Roswitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766736/
https://www.ncbi.nlm.nih.gov/pubmed/26362758
http://dx.doi.org/10.1136/annrheumdis-2015-207548