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Efficient therapy of ischaemic lesions with VEGF(121)-fibrin in an animal model of systemic sclerosis
BACKGROUND: In systemic sclerosis (SSc), chronic and uncontrolled overexpression of vascular endothelial growth factor (VEGF) results in chaotic vessels, and intractable fingertip ulcers. Vice versa, VEGF is a potent mediator of angiogenesis if temporally and spatially controlled. We have addressed...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766736/ https://www.ncbi.nlm.nih.gov/pubmed/26362758 http://dx.doi.org/10.1136/annrheumdis-2015-207548 |