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IL-17 Induction by ArtinM is Due to Stimulation of IL-23 and IL-1 Release and/or Interaction with CD3 in CD4(+) T Cells

ArtinM is a D-mannose-binding lectin extracted from the seeds of Artocarpus heterophyllus that interacts with TLR2 N-glycans and activates antigen-presenting cells (APCs), as manifested by IL-12 production. In vivo ArtinM administration induces Th1 immunity and confers protection against infection w...

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Detalles Bibliográficos
Autores principales: da Silva, Thiago Aparecido, Mariano, Vania Sammartino, Sardinha-Silva, Aline, de Souza, Maria Aparecida, Mineo, Tiago Wilson Patriarca, Roque-Barreira, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767177/
https://www.ncbi.nlm.nih.gov/pubmed/26901413
http://dx.doi.org/10.1371/journal.pone.0149721