Cargando…

Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age

Differentiating pluripotent cells from fibroblast progenitors is a potentially transformative tool in personalized medicine. We previously identified relatively greater success culturing dura-derived fibroblasts than scalp-derived fibroblasts from postmortem tissue. We hypothesized that these differ...

Descripción completa

Detalles Bibliográficos
Autores principales: Ivanov, Nikolay A., Tao, Ran, Chenoweth, Joshua G., Brandtjen, Anna, Mighdoll, Michelle I., Genova, John D., McKay, Ronald D., Jia, Yankai, Weinberger, Daniel R., Kleinman, Joel E., Hyde, Thomas M., Jaffe, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767228/
https://www.ncbi.nlm.nih.gov/pubmed/26913521
http://dx.doi.org/10.1371/journal.pgen.1005819