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Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer

Although the role of acyl-CoA synthetase 4 (ACSL4) in mediating an aggressive phenotype is well accepted, there is little evidence as to the early steps through which ACSL4 increases tumor growth and progression. In this study, and by means of the stable transfection of MCF-7 cells with ACSL4 using...

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Detalles Bibliográficos
Autores principales: Orlando, Ulises D., Castillo, Ana F., Dattilo, Melina A., Solano, Angela R., Maloberti, Paula M., Podesta, Ernesto J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767459/
https://www.ncbi.nlm.nih.gov/pubmed/26536660