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β-arrestin drives MAP kinase signaling from clathrin-coated structures after GPCR dissociation

β-arrestins critically regulate G protein-coupled receptor (GPCR) signaling, not only 'arresting' the G protein signal but also modulating endocytosis and initiating a discrete G protein-independent signal via MAP kinase(1–3). Despite enormous recent progress toward understanding biophysic...

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Detalles Bibliográficos
Autores principales: Eichel, K., Jullié, D., von Zastrow, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767649/
https://www.ncbi.nlm.nih.gov/pubmed/26829388
http://dx.doi.org/10.1038/ncb3307