Cargando…
β-arrestin drives MAP kinase signaling from clathrin-coated structures after GPCR dissociation
β-arrestins critically regulate G protein-coupled receptor (GPCR) signaling, not only 'arresting' the G protein signal but also modulating endocytosis and initiating a discrete G protein-independent signal via MAP kinase(1–3). Despite enormous recent progress toward understanding biophysic...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767649/ https://www.ncbi.nlm.nih.gov/pubmed/26829388 http://dx.doi.org/10.1038/ncb3307 |