Folate Acts in E. coli to Accelerate C. elegans Aging Independently of Bacterial Biosynthesis

Folates are cofactors for biosynthetic enzymes in all eukaryotic and prokaryotic cells. Animals cannot synthesize folate and must acquire it from their diet or microbiota. Previously, we showed that inhibiting E. coli folate synthesis increases C. elegans lifespan. Here, we show that restriction or...

Descripción completa

Detalles Bibliográficos
Autores principales: Virk, Bhupinder, Jia, Jie, Maynard, Claire A., Raimundo, Adelaide, Lefebvre, Jolien, Richards, Shane A., Chetina, Natalia, Liang, Yen, Helliwell, Noel, Cipinska, Marta, Weinkove, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767678/
https://www.ncbi.nlm.nih.gov/pubmed/26876180
http://dx.doi.org/10.1016/j.celrep.2016.01.051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767678/
https://www.ncbi.nlm.nih.gov/pubmed/26876180
http://dx.doi.org/10.1016/j.celrep.2016.01.051

Ejemplares similares