Phosphate–Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1

Tubulo-interstitial fibrosis is a common, destructive endpoint for a variety of kidney diseases. Fibrosis is well correlated with the loss of kidney function in both humans and rodents. The identification of modulators of fibrosis could provide novel therapeutic approaches to reducing disease progre...

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Detalles Bibliográficos
Autores principales: Shen, Zhong-Jian, Hu, Jie, Shiizaki, Kazuhiro, Kuro-o, Makoto, Malter, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767802/
https://www.ncbi.nlm.nih.gov/pubmed/26914452
http://dx.doi.org/10.1371/journal.pone.0150093