Analysis of the Putative Role of CR1 in Alzheimer’s Disease: Genetic Association, Expression and Function

Chronic activation of the complement system and induced inflammation are associated with neuropathology in Alzheimer’s disease (AD). Recent large genome wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) in the C3b/C4b receptor (CR1 or CD35) that are associated wi...

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Detalles Bibliográficos
Autores principales: Fonseca, Maria I., Chu, Shuhui, Pierce, Aimee L., Brubaker, William D., Hauhart, Richard E., Mastroeni, Diego, Clarke, Elizabeth V., Rogers, Joseph, Atkinson, John P., Tenner, Andrea J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767815/
https://www.ncbi.nlm.nih.gov/pubmed/26914463
http://dx.doi.org/10.1371/journal.pone.0149792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767815/
https://www.ncbi.nlm.nih.gov/pubmed/26914463
http://dx.doi.org/10.1371/journal.pone.0149792

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