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FOXO1 inhibits osteosarcoma oncogenesis via Wnt/β-catenin pathway suppression
Recent advances have highlighted profound roles of FOXO transcription factors, especially FOXO1, in bone development and remodeling. The regulation of bone development by FOXOs seems to be stage-specific or context dependent. FOXOs promote maintenance and differentiation of early progenitors of the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767937/ https://www.ncbi.nlm.nih.gov/pubmed/26344693 http://dx.doi.org/10.1038/oncsis.2015.25 |