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FOXO1 inhibits osteosarcoma oncogenesis via Wnt/β-catenin pathway suppression

Recent advances have highlighted profound roles of FOXO transcription factors, especially FOXO1, in bone development and remodeling. The regulation of bone development by FOXOs seems to be stage-specific or context dependent. FOXOs promote maintenance and differentiation of early progenitors of the...

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Detalles Bibliográficos
Autores principales: Guan, H, Tan, P, Xie, L, Mi, B, Fang, Z, Li, J, Yue, J, Liao, H, Li, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767937/
https://www.ncbi.nlm.nih.gov/pubmed/26344693
http://dx.doi.org/10.1038/oncsis.2015.25