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Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer

The forkhead transcription factor FOXK2 has recently been implicated in cancer cell proliferation and survival, but a role in cancer chemotherapeutic drug resistance has hitherto not been explored. Here we demonstrate that FOXK2 has a central role in mediating the cytotoxic drug response in breast c...

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Detalles Bibliográficos
Autores principales: de Moraes, G Nestal, Khongkow, P, Gong, C, Yao, S, Gomes, A R, Ji, Z, Kandola, N, Delbue, D, Man, E P S, Khoo, U S, Sharrocks, A D, Lam, E W-F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767938/
https://www.ncbi.nlm.nih.gov/pubmed/26344694
http://dx.doi.org/10.1038/oncsis.2015.26