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Inhibition of Sprouty2 polarizes macrophages toward an M2 phenotype by stimulation with interferon γ and Porphyromonas gingivalis lipopolysaccharide

Periodontitis is a chronic inflammatory disorder caused by specific bacteria residing in the biofilm, particularly Porphyromonas gingivalis (Pg). Sprouty2 (Spry2) functions as a negative regulator of the fibroblast growth factor (FGF) signaling pathway. We previously demonstrated that sequestration...

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Detalles Bibliográficos
Autores principales: Atomura, Ryo, Sanui, Terukazu, Fukuda, Takao, Tanaka, Urara, Toyoda, Kyosuke, Taketomi, Takaharu, Yamamichi, Kensuke, Akiyama, Hajime, Nishimura, Fusanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768065/
https://www.ncbi.nlm.nih.gov/pubmed/27042307
http://dx.doi.org/10.1002/iid3.99