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Differential changes in gene expression in human neutrophils following TNF‐α stimulation: Up‐regulation of anti‐apoptotic proteins and down‐regulation of proteins involved in death receptor signaling

Responses of human neutrophils to TNF‐α are complex and multifactorial. Exposure of human neutrophils to TNF‐α in vitro primes the respiratory burst, delays apoptosis and induces the expression of several genes including chemokines, and TNF‐α itself. This study aimed to determine the impact of TNF‐α...

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Detalles Bibliográficos
Autores principales: Chiewchengchol, Direkrit, Wright, Helen L., Thomas, Huw B., Lam, Connie W., Roberts, Kate J., Hirankarn, Nattiya, Beresford, Michael W., Moots, Robert J., Edwards, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768069/
https://www.ncbi.nlm.nih.gov/pubmed/27042300
http://dx.doi.org/10.1002/iid3.90