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Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish

The Adverse Outcome Pathway (AOP) framework represents a valuable conceptual tool to systematically integrate existing toxicological knowledge from a mechanistic perspective to facilitate predictions of chemical-induced effects across species. However, its application for decision-making requires th...

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Detalles Bibliográficos
Autores principales: Margiotta-Casaluci, Luigi, Owen, Stewart F., Huerta, Belinda, Rodríguez-Mozaz, Sara, Kugathas, Subramanian, Barceló, Damià, Rand-Weaver, Mariann, Sumpter, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768075/
https://www.ncbi.nlm.nih.gov/pubmed/26917256
http://dx.doi.org/10.1038/srep21978