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Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish
The Adverse Outcome Pathway (AOP) framework represents a valuable conceptual tool to systematically integrate existing toxicological knowledge from a mechanistic perspective to facilitate predictions of chemical-induced effects across species. However, its application for decision-making requires th...
Autores principales: | Margiotta-Casaluci, Luigi, Owen, Stewart F., Huerta, Belinda, Rodríguez-Mozaz, Sara, Kugathas, Subramanian, Barceló, Damià, Rand-Weaver, Mariann, Sumpter, John P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768075/ https://www.ncbi.nlm.nih.gov/pubmed/26917256 http://dx.doi.org/10.1038/srep21978 |
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