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Substrate-dependent dynamics of the multidrug efflux transporter AcrB of Escherichia coli

The resistance-nodulation-cell division (RND)-type xenobiotic efflux system plays a major role in the multidrug resistance of gram-negative bacteria. The only constitutively expressed RND system of Escherichia coli consists of the inner membrane transporter AcrB, the membrane fusion protein AcrA, an...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kentaro, Tamai, Rei, Yamazaki, Megumi, Inaba, Takehiko, Sowa, Yoshiyuki, Kawagishi, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768149/
https://www.ncbi.nlm.nih.gov/pubmed/26916090
http://dx.doi.org/10.1038/srep21909