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Substrate-dependent dynamics of the multidrug efflux transporter AcrB of Escherichia coli
The resistance-nodulation-cell division (RND)-type xenobiotic efflux system plays a major role in the multidrug resistance of gram-negative bacteria. The only constitutively expressed RND system of Escherichia coli consists of the inner membrane transporter AcrB, the membrane fusion protein AcrA, an...
Autores principales: | Yamamoto, Kentaro, Tamai, Rei, Yamazaki, Megumi, Inaba, Takehiko, Sowa, Yoshiyuki, Kawagishi, Ikuro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768149/ https://www.ncbi.nlm.nih.gov/pubmed/26916090 http://dx.doi.org/10.1038/srep21909 |
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