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Evidence for genetic association of TBX21 and IFNG with systemic lupus erythematosus in a Chinese Han population

TBX21 recode T-bet which is an important transcription factor that drives the Th1 immune response primarily by promoting expression of the interferon-gamma (IFNG) gene. Recent studies have shown that genetic variants in TBX21 and IFNG are connected with risk of systemic lupus erythematosus (SLE). Th...

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Detalles Bibliográficos
Autores principales: Leng, Rui-Xue, Pan, Hai-Feng, Liu, Juan, Yang, Xiao-Ke, Zhang, Chao, Tao, Sha-Sha, Wang, De-Guang, Li, Xiao-Mei, Li, Xiang-Pei, Yang, Wanling, Ye, Dong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768161/
https://www.ncbi.nlm.nih.gov/pubmed/26916970
http://dx.doi.org/10.1038/srep22081