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Evidence for genetic association of TBX21 and IFNG with systemic lupus erythematosus in a Chinese Han population
TBX21 recode T-bet which is an important transcription factor that drives the Th1 immune response primarily by promoting expression of the interferon-gamma (IFNG) gene. Recent studies have shown that genetic variants in TBX21 and IFNG are connected with risk of systemic lupus erythematosus (SLE). Th...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768161/ https://www.ncbi.nlm.nih.gov/pubmed/26916970 http://dx.doi.org/10.1038/srep22081 |