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A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate

Three important physical properties which may affect the performance of glycoconjugate vaccines against serious disease are molar mass (molecular weight), heterogeneity (polydispersity), and conformational flexibility in solution. The dilute solution behaviour of native and activated capsular polyri...

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Detalles Bibliográficos
Autores principales: Abdelhameed, Ali Saber, Adams, Gary G., Morris, Gordon A., Almutairi, Fahad M., Duvivier, Pierre, Conrath, Karel, Harding, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768162/
https://www.ncbi.nlm.nih.gov/pubmed/26915577
http://dx.doi.org/10.1038/srep22208