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A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate
Three important physical properties which may affect the performance of glycoconjugate vaccines against serious disease are molar mass (molecular weight), heterogeneity (polydispersity), and conformational flexibility in solution. The dilute solution behaviour of native and activated capsular polyri...
Autores principales: | Abdelhameed, Ali Saber, Adams, Gary G., Morris, Gordon A., Almutairi, Fahad M., Duvivier, Pierre, Conrath, Karel, Harding, Stephen E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768162/ https://www.ncbi.nlm.nih.gov/pubmed/26915577 http://dx.doi.org/10.1038/srep22208 |
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