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Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure

The rat is an important model for liver regeneration. However, there is no in vitro culture system that can capture the massive proliferation that can be observed after partial hepatectomy in rats. We here describe the generation of rat liver stem cell lines. Rat liver stem cells, which grow as cyst...

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Detalles Bibliográficos
Autores principales: Kuijk, Ewart W., Rasmussen, Shauna, Blokzijl, Francis, Huch, Meritxell, Gehart, Helmuth, Toonen, Pim, Begthel, Harry, Clevers, Hans, Geurts, Aron M., Cuppen, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768167/
https://www.ncbi.nlm.nih.gov/pubmed/26915950
http://dx.doi.org/10.1038/srep22154