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Rab6a is a novel regulator of meiotic apparatus and maturational progression in mouse oocytes

Rab family GTPases have been well known to regulate intracellular vesicle transport, however their function in mammalian oocytes has not been addressed. In this study, we report that when Rab6a is specifically knockdown, mouse oocytes are unable to progress normally through meiosis, arresting at met...

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Detalles Bibliográficos
Autores principales: Hou, Xiaojing, Zhang, Jiaqi, Li, Ling, Ma, Rujun, Ge, Juan, Han, Longsen, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768169/
https://www.ncbi.nlm.nih.gov/pubmed/26915694
http://dx.doi.org/10.1038/srep22209