Subcellular localization of anthracyclines in cultured rat cardiomyoblasts as possible predictors of cardiotoxicity

In this study, we compared the cellular uptake, intracellular localization and cytotoxicity of two groups of anthracycline derivatives in cultured H9c2(2-1) rat cardiomyoblasts. The first group consisted of doxorubicin (DOX) and two of its derivatives containing a formamidino group (–N = CH–N<) a...

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Detalles Bibliográficos
Autores principales: Studzian, Kazimierz, Kik, Krzysztof, Lukawska, Malgorzata, Oszczapowicz, Irena, Strek, Malgorzata, Szmigiero, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Preclinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768221/
https://www.ncbi.nlm.nih.gov/pubmed/26268925
http://dx.doi.org/10.1007/s10637-015-0276-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768221/
https://www.ncbi.nlm.nih.gov/pubmed/26268925
http://dx.doi.org/10.1007/s10637-015-0276-9

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