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The metastasis-inducing protein AGR2 is O-glycosylated upon secretion from mammary epithelial cells

AGR2 is overexpressed in multiple cancers, particularly those arising from breast and prostate tissues, and higher levels of AGR2 are associated with earlier patient death. Although AGR2 is normally resident within the endoplasmic reticulum, the protein has been found in the extracellular space in s...

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Detalles Bibliográficos
Autores principales: Clarke, Christopher, Rudland, Philip, Barraclough, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768226/
https://www.ncbi.nlm.nih.gov/pubmed/26169982
http://dx.doi.org/10.1007/s11010-015-2502-3