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The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells

New strategy of cancer’s targeting treatment is combining monoclonal antibodies with chemotherapeutic agents. An important goal of targeted therapy appears to be a transmembrane glycoprotein type I—mucin 1 (MUC1), which is overexpressed in tumors of epithelial origin, especially in breast cancer. Th...

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Detalles Bibliográficos
Autores principales: Gornowicz, Agnieszka, Bielawska, Anna, Czarnomysy, Robert, Gabryel-Porowska, Halina, Muszyńska, Anna, Bielawski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768227/
https://www.ncbi.nlm.nih.gov/pubmed/26112902
http://dx.doi.org/10.1007/s11010-015-2486-z